❖ Transcription factors are special proteins that help read the information in our DNA.

❖ They attach to the specific regions of the DNA and start a process called the transcription, which copies genetic information from DNA to RNA.

❖ New research found that the fate of a gene being transcribed depends on the location of the transcription factor binding site relative to the location where transcription begins.

❖ This provides insights into how different spatial arrangements of the same transcription factors can have different effects.

❖ The findings can “help filter and refine genomic tools and algorithms that predict gene expression”.